Epstein-Barr virus (EBV) infects over 90% of humans and can lead to cancers such as Hodgkin’s, Burkitt’s, and AIDS-related lymphomas. The connections between EBV and cancer are not well understood. This project will explore molecular structure in EBV as a potential source of its cancer-causing properties. Additionally, this work will advance the development of novel cancer therapeutics that target EBV molecular structures. Please follow the project link and consider donating. Thank you!
Can viral molecular structures cause cancer?
- EBV Noncoding RNA Binds Nascent RNA to Drive Host PAX5 to Viral DNA
- High-Throughput RNA sequencing based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project
- Secondary Structure of a Conserved Domain in an Intron of Influenza A M1 mRNA
- Structural insights into the stabilization of MALAT1 noncoding RNA by a bipartite triple helix
EBER2 is an abundant nuclear noncoding RNA expressed by the Epstein-Barr virus (EBV). Probing its possible chromatin localization by CHART revealed EBER2’s presence at the…
High-Throughput RNA sequencing based virome analysis of 50 lymphoma cell lines from the Cancer Cell Line Encyclopedia project
Using high-throughput RNA sequencing (RNA-seq) data from 50 common lymphoma cell culture models from the Cancer Cell Line Encyclopedia project, we performed an unbiased…
Want to learn about how luck can favor a prepared mind and lead to discovery/innovation? Watch this awesome video of my mentor:
Influenza A virus utiizes RNA throughout infection. Little is known, however, about the roles of RNA structures in these processes. A previous bioinformatics survey predicted…